• 有機触媒を用いた（−）‐オセルタミビルの３ポット合成
  ファインケミカル, 39, 5 (2010).                                                                                                                                               H. Ishikawa, and Y. Hayashi

• One-pot synthesis of chiral bicyclo[3.3.0]octatrienes using diphenylprolinol silyl ether-mediated ene-type reaction

  Tetrahedron, ASAP.
  H. Gotoh, H. Ogino, H. Ishikawa, and Y. Hayashi

                              

• Syntheses of Fumagillin and Ovalicin
  Chem. Eur. J., ASAP.
  J. Yamaguchi, and Y. Hayashi
                            

• インフルエンザ治療薬オセルタミビルの３ポット合成　―ジフェニルプロリノールシリルエーテル触媒を用いた全合成―                 化学と生物, 48, 156 (2010).                                            　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　         

  H. Ishikawa, and Y. Hayashi

• Prof. Hayashi is invited as plenary lecturer at 11th International Conference on the Chemistry of Antibiotics and Other Bioactive Compounds, San Sebastian, Spaines on September 29‐October 2, 2009.

• Prof. Hayashi is an invited speaker at Microsymposium on Asymmetric Synthesis, Warsaw (Institute of Organic Chemistry, Polish Academy of Sciences) on September 18, 2009.

• Most cited paper published in Angew. Chem. Int. Ed. from 2006 to 2007
  Rank 2nd and 19th

• Diphenylprolinol Silyl Ether as a Catalyst in an Asymmetric, Catalytic, and Direct Michael Reaction of Nitroethanol with α,β-Unsaturated Aldehydes
  Org. Lett.,11, 4056 (2009).
  Hiroaki Gotoh, Daichi Okamura, Hayato Ishikawa, and Yujiro Hayashi
                                                        
• Small organic molecule in enantioselective, direct aldol reaction in water

  Chem. Commun., 2524 (2007).
  S. Aratake, T. Itoh, T. Okano, T. Usui, M. Shoji and Y. Hayashi       
  Make an impact at the top 50 articles, published in 2007.
  
  

• Dry and Wet Prolines for Asymmetric Organic-Solvent-Free Aldehyde-Aldehyde and Aldehyde-Ketone Aldol Reactions

  Chem. Commun., 957 (2007).
  Y. Hayashi, S. Aratake, T. Itoh, T. Okano, T. Sumiya, M. Shoji       
  Make an impact at the top 20 articles, published in 2007.
  
  

• Structures of the Reactive Intermediates in Organocatalysis with Diarylprolinol Ethers
  Helvetica Chimica Acta., 92, 1225 (2009).
  Uros Groselj, Dieter Seebach, D. Michael Badine, W. Bernd Schweizer, Albert K. Beck, Ingo Krossing, Petra Klose, Yujiro Hayashi, Tadafumi Uchimaru

• Asymmetric Aldol Reaction of Acetaldehyde and Isatin Derivatives for the Total Syntheses of ent-Convolutamydine E and CPC-1 and a Half Fragment of Madindoline A and B
  Org. Lett.,11, 3854 (2009).
  Takahiko Itoh, Hayato Ishikawa, and Yujiro Hayashi
  
                                                                                    
  
  
  
  
• Diphenylprolinol silyl ether as a catalyst in an asymmetric, catalytic and direct - benzoyloxylation of aldehydes
  Chem. Commun, 3083 (2009).
   H. Gotoh, Y. Hayashi

• Prof. Hayashi is an invited speaker at National Organic Symposium Trust
  XIII Organic Chemistry Conference at Majorda Beach Resort, Goa (May 1 - 4, 2009)
  
  
• The following 5 papers are selected in SYNFACTS
  SYNFACTS 2009, 327
  SYNFACTS 2009, 247
  SYNFACTS 2008, 899
  SYNFACTS 2008, 764
  SYNFACTS 2008, 762
  SYNFACTS 2008, 533
  
  
• Prof. Hayashi received "SSOCJ Daiichi-Sankyo Award for Medicinal Organic Chemistry 2008"
  (2008年度有機合成化学協会 第一三共・創薬有機化学賞)

• High-Yielding Synthesis of the Anti-Influenza Neuramidase Inhibitor (−)-Oseltamivir by Three "One-Pot" Operations

        Angew. Chem. Int. Ed., 48, 1304 (2009).
        Hayato Ishikawa, Takaki Suzuki, Yujiro Hayashi       
        Abstracted in Resarch Highlights of Nature 457, 239
        Abstracted in Science-Business eXchange Vol. 2 / No. 4 Jan. 2009
        Abstracted in CHEMISTRY TODAY (現代化学）No. 456 March. 2009
        Most accessed articles in 01/2009 : Ranked as 1st!

• Diphenylprolinol Silyl Ether as a Catalyst in an Enantioselective, Catalytic Michael Reaction for the Formation of ,-Disubstituted -Amino Acid Derivatives
  
  Chem. Asian. J., 4, 246 (2009).
  
  

  Yujiro Hayashi, Kazuki Obi, Yusuke Ohta, Daichi Okamura, Hayato Ishikawa
                                                       

• Diphenylprolinol Silyl Ether Catalysis in an Asymmetric Formal Carbo [3 + 3] Cycloaddition Reaction via a Domino Michael/Knoevenagel Condensation
  
  Org. Lett., 11, 45 (2009).

  Yujiro Hayashi, Maya Toyoshima, Hiroaki Gotoh and Hayato Ishikawa

• Asymmetric, Catalytic, and Direct Self-Aldol Reaction of Acetaldehyde Catalyzed by Diarylprolinol
  Org. Lett.,10, 5581, (2008).
  Yujiro Hayashi, Sampak Samanta, Takahiko Itoh and Hayato Ishikawa
  
                                  
  
  
• Direct Organocatalytic Mannich Reaction of Acetaldehyde: An Improved Catalyst and Mechanistic Insight from a Computational Study
  Angew. Chem. Int. Ed.,47, 9053 (2008).
  Yujiro Hayashi, Tsubasa Okano, Takahiko Itoh, Tatsuya Urushima, Hayato Ishikawa, Tadafumi Uchimaru
  
                                       
  
  
  
• The Asymmetric Total Synthesis of (+)-Cytotrienin A, an Ansamycin-Type Anticancer Drug
  Angew. Chem. Int. Ed.,47, 6657 (2008).
  Yujiro Hayashi, Mitsuru Shoji, Hayato Ishikawa, Junichiro Yamaguchi, Tomohiro Tamura, Hiroki Imai,
  Yosuke Nishigaya^, Kenichi Takabe, Hideaki Kakeya, Hiroyuki Osada
  
                                         
  
  
• Asymmetric Diels-Alder Reactions of ,-Unsaturated Aldehydes Catalyzed by a Diarylprolinol Silyl Ether Salt in the Presence of Water
  Angew. Chem. Int. Ed.,47, 6634 (2008).
  Yujiro Hayashi, Sampak Samanta, Hiroaki Gotoh, Hayato Ishikawa
  
                                                     
   
  
• Asymmetric Michael Reaction of Acetaldehyde Catalyzed by Diphenylprolinol Silyl Ether)
  Angew. Chem. Int. Ed.,47, 4722 (2008).
  Yujiro Hayashi, Takahiko Itoh, Masahiro Ohkubo, Hayato Ishikawa
  

  

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